Zaldaride maleate
| Chemical Name | Zaldaride maleate |
|---|---|
| CAS Number | 109826-27-9 |
| MDL Number | MFCD04113002 |
| Molecular Formula | C30H32N4O6 |
| Molecular Weight | 544.60 |
| Synonyms | CGS-9343B;KW 5617 |
Introduction of 109826-27-9 :
Zaldaride maleate (CGS-9343B) is a potent, orally active and selective inhibitor of calmodulin. Zaldaride maleate (CGS-9343B) inhibits CaM (calmodulin)-stimulated cAMP phosphodiesterase activity, with an IC50 of 3.3 nM[1][2]. Zaldaride maleate (CGS-9343B) prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR[3]. IC50 & Target: IC50: 3.3 nM (calmodulin)[1][2]. In Vivo: Zaldaride maleate (KW 5617, P.O., 3 mg/kg) ameliorates the diarrhea in the 16, 16-dimethyl prostaglandin E2 model[4].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.