Zaldaride maleate
| 화학 이름 | Zaldaride maleate |
|---|---|
| CAS 번호 | 109826-27-9 |
| MDL 번호 | MFCD04113002 |
| 분자식 | C30H32N4O6 |
| 분자 무게 | 544.60 |
| 동의어 | CGS-9343B;KW 5617 |
Introduction of 109826-27-9 :
Zaldaride maleate (CGS-9343B) is a potent, orally active and selective inhibitor of calmodulin. Zaldaride maleate (CGS-9343B) inhibits CaM (calmodulin)-stimulated cAMP phosphodiesterase activity, with an IC50 of 3.3 nM[1][2]. Zaldaride maleate (CGS-9343B) prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR[3]. IC50 & Target: IC50: 3.3 nM (calmodulin)[1][2]. In Vivo: Zaldaride maleate (KW 5617, P.O., 3 mg/kg) ameliorates the diarrhea in the 16, 16-dimethyl prostaglandin E2 model[4].
| 청정 | NLT 98% |
|---|---|
| 저장 | at 20ºC 2 years |
*위의 정보는 참고 용입니다.