4-Ethynyl-L-phenylalanine
| 화학 이름 | 4-Ethynyl-L-phenylalanine |
|---|---|
| 화학 이름 | 4-Ethynyl-L-phenylalanine |
| CAS 번호 | 278605-15-5 |
| 분자식 | C11H11NO2 |
| 분자 무게 | 189.21 |
Introduction of 278605-15-5 :
4-Ethynyl-L-phenylalanine is a selective, reversible, potent and competitive inhibitor of tryptophan hydroxylase (TPH). 4-Ethynyl-L-phenylalanine is a competitive inhibitor with regard to the substrate tryptophan, with a Ki of 32.6 μM. 4-Ethynyl-L-phenylalanine selectively and reversibly inhibits the biosynthesis of serotonin[1]. IC50 & Target: Ki: 32.6 μM (TPH)[1] In Vivo: 4-Ethynyl-L-phenylalanine (30 mg/kg; i.p.) decreases in 5-HT and 5-HIAA levels in the rat midbrain but not in tissue[1].
4-Ethynyl-L-phenylalanine is not inhibiting the aromatic amino acid decarboxylase[1].
4-Ethynyl-L-phenylalanine has a low affinity for various recombinant 5-HT receptors[1].
| 청정 | NLT 98% |
|---|---|
| 저장 | at 20ºC 2 years |
*위의 정보는 참고 용입니다.