CAS No. 187724-61-4, PKI-166

PKI-166

NLT 98%
187724-61-4
DY535069
PKI-166
C20H18N4O
330.38

견적 요청

화학 이름 PKI-166
화학 이름 PKI-166
CAS 번호 187724-61-4
MDL 번호 MFCD09970842
분자식 C20H18N4O
분자 무게 330.38
Introduction of 187724-61-4 :

PKI-166 is a potent, selective and orally bioavailable EGFR tyrosine kinase inhibitor, with an IC50 of 0.7 nM[1]. IC50 & Target: IC50: 0.7 nM (EGFR tyrosine kinase)[1] In Vitro: Pretreatment with PKI-166 (0–0.5 μM; 1 hour) inhibits EGFR autophosphorylation in human pancreatic cancer cells[1].
PKI-166 (0.03μ M; 6 days) enhanced the cytotoxicity mediated by gemcitabine[1].
In Vivo: PKI-166 (100 mg/kg; p.o.; daily; day 7-day 35 after xenograft) inhibits of pancreatic cancer growth[1].

청정 NLT 98%
저장 at 20ºC 2 years
*위의 정보는 참고 용입니다.

견적 요청

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