EFDA
865363-93-5
DY445203
C12H12FN5O3
293.25
MK-8591;Islatravir;4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine
| Chemical Name | EFDA |
|---|---|
| CAS Number | 865363-93-5 |
| Molecular Formula | C12H12FN5O3 |
| Molecular Weight | 293.25 |
| Synonyms | MK-8591;Islatravir;4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine |
Islatravir (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively.
| Appearance | White to Off-white powder |
|---|---|
| Purity | NLT 98% |
| Boiling Point | 669.2±65.0 ºC at 760 mmHg |
| Flash Point | 358.5±34.3 ºC |
| Storage | tightly closed,keep in a dry,well-ventilated place. |
*The above information is for reference only.
| Symbol |
GHS07
|
|---|---|
| Signal word | Warning |
| Hazard statements | H302;H315;H319;H335 |
| Precautionary statements | P261;P305+P351+P338 |