CAS No. 865363-93-5, EFDA

EFDA

NLT 95%
865363-93-5
DY445203
C12H14FN5O3
295.2697
MK-8591;Islatravir;(2R,3S,5R)-5-(6-amino-2-fluoro-4H-purin-9(5H)-yl)-2-ethynyl-2-(hydroxymethyl)-tetrahydrofuran-3-ol
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DY445203-1g

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Chemical Name EFDA
CAS Number 865363-93-5
Molecular Formula C12H14FN5O3
Molecular Weight 295.2697
Synonyms MK-8591;Islatravir;(2R,3S,5R)-5-(6-amino-2-fluoro-4H-purin-9(5H)-yl)-2-ethynyl-2-(hydroxymethyl)-tetrahydrofuran-3-ol
Islatravir (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively.
Appearance White to Off-white powder
Purity NLT 95%
Boiling Point 669.2±65.0 ºC at 760 mmHg
Flash Point 358.5±34.3 ºC
Storage tightly closed,keep in a dry,well-ventilated place.
*The above information is for reference only.
Symbol GHS07
Signal word Warning
Hazard statements H302;H315;H319;H335
Precautionary statements P261;P305+P351+P338

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