Chemical Name |
Sinensetin |
CAS Number |
2306-27-6 |
MDL Number |
MFCD00017421 |
Molecular Formula |
C20H20O7 |
Molecular Weight |
372.37 |
Synonyms |
Pedalitin permethyl ether |
Introduction of 2306-27-6 :
Sinensetin is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis. In vitro: Sinensetin promots adipogenesis in 3T3-L1 preadipocytes growing in incomplete differentiation medium, sinensetin enhances adipogenesis and lipolysis by increasing cAMP levels. [1] Sinensetin shows anti-inflammatory activity by regulating the protein level of inhibitor κB-α (IκB-α). [2] In vivo: Sinensetin has the most potent antiangiogenesis activity and the lowest toxicity, inhibits angiogenesis by inducing cell cycle arrest in the G0/G1 phase in HUVEC culture and downregulating the mRNA expressions of angiogenesis genes flt1, kdrl, and hras in zebrafish. [3]
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.