Chemical Name |
5-Aminouridine |
CAS Number |
2149-76-0 |
Molecular Formula |
C9H13N3O6 |
Molecular Weight |
259.22 |
Introduction of 2149-76-0 :
5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses[1][2][3]. In Vitro: This modified nucleobase, 5-Aminouridine, must exhibit a low enough potential to be oxidized by Os(bpy)33+. These modified nucleobases can be inserted into the target DNA by direct synthesis using modified phosphoramidites[4]. In Vivo: 5-Aminouridine inhibits incorporation of carbamylaspartate into pyrimidines of both RNA and DNA in rat lived and [32P]phosphate into phospholipids and RNA nucleotides of rat liver slices and hepatoma[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.