Chemical Name |
Bupivacaine (hydrochloride) |
CAS Number |
18010-40-7 |
MDL Number |
MFCD00078956 |
Molecular Formula |
C18H29ClN2O |
Molecular Weight |
324.89 |
Introduction of 18010-40-7 :
Bupivacaine Hydrochloride is a local anaesthetic drug belonging to the amino amide group. Target: Others Bupivacaine hydrochloride is an effective local anesthetic agent. It has a rapid onset time, a high frequency of surgical anesthesia, a long duration, and a low incidence of side effects [1]. Median doses of bupivacaine (in milligrams per kilogram) producing asystole in protocol 1 were for 17.7 for saline, 27.6 for 10% Intralipid, 49.7 for 20% Intralipid, and 82.0 for 30% Intralipid (P < 0.001 for differences between all groups). Differences in mean +/- SE concentrations of bupivacaine in plasma (in micrograms per milliliter) were significant (P < 0.05) for the difference between saline (93.3 +/- 7.6) and 30% Intralipid (212 +/- 45). In protocol 2, lipid infusion increased the dose of bupivacaine required to cause death in 50% of animals by 48%, from 12.5 to 18.5 mg/kg. The mean lipid:aqueous ratio of concentrations of bupivacaine in a plasma-Intralipid mixture was 11.9 +/- 1.77 (n = 3) [2].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.