Chemical Name |
Trimethobenzamide |
CAS Number |
138-56-7 |
MDL Number |
MFCD00599601 |
Molecular Formula |
C21H28N2O5 |
Molecular Weight |
388.46 |
Synonyms |
Emedur |
Introduction of 138-56-7 :
Trimethobenzamide is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting. IC50 & Target: D2 receptor[1] In Vitro: Trimethobenzamide is a (non-phenothiazine) benzamide antiemetic that acts centrally to block D2 receptors, thereby inhibiting the medullary chemoreceptor trigger zone by blocking emetic impulses to the vomiting center[1]. In Vivo: The oral bioavailability of Trimethobenzamide is 60% to 100%. The time to peak is about 45 minutes after oral administration and; Intramuscular (I.M.) administration about 30 minutes after intramuscular administration[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.