CAS No. 137417-08-4, Dihydrexidine (hydrochloride)

Dihydrexidine (hydrochloride)

NLT 98%
DAR-0100 (hydrochloride)

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Chemical Name Dihydrexidine (hydrochloride)
CAS Number 137417-08-4
MDL Number MFCD01860859
Molecular Formula C17H18ClNO2
Molecular Weight 303.78
Synonyms DAR-0100 (hydrochloride)
Introduction of 137417-08-4 :

Dihydrexidine hydrochloride (DAR-0100 hydrochloride) is a high potent, selective and full efficacy D1-like dopamine receptor (D1/D5) agonist, with an IC50 of 10 nM for D1 receptor. Dihydrexidine hydrochloride exhibits potent antiparkinsonian activity[1][2][3][4]. IC50 & Target: IC50: 10 nM (D1 dopamine receptor), D5 dopamine receptor, 660 nM (D2 dopamine receptor)[1] In Vivo: Dihydrexidine hydrochloride has poor oral bioavailability and a relatively short half-life of 1 to 2 h[3].
Dihydrexidine hydrochloride (3 mg/kg; i.p.) produces prominent dopamine D1 receptor agonist effects in vivo[4].

Purity NLT 98%
Storage at 20ºC 2 years
*The above information is for reference only.

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