CAS No. 15966-93-5, SU5408

SU5408

NLT 98%
15966-93-5
DY528270
SU5408
C18H18N2O3
310.35
VEGFR2 Kinase Inhibitor I

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화학 이름 SU5408
화학 이름 SU5408
CAS 번호 15966-93-5
MDL 번호 MFCD13191286
분자식 C18H18N2O3
분자 무게 310.35
동의어 VEGFR2 Kinase Inhibitor I
Introduction of 15966-93-5 :

SU5408 (VEGFR2 Kinase Inhibitor I) is a potent and cell-permeable inhibitor of VEGFR2 kinase with an IC50 of 70 nM. IC50 & Target: IC50: 70 nM (VEGFR2)[1] In Vitro: 3-Substituted indolin-2-ones have been designed and synthesized as a novel class of tyrosine kinase inhibitors which exhibit selectivity toward different receptor tyrosine kinases (RTKs). These compounds have been evaluated for their relative inhibitory properties against a panel of RTKs in intact cells. SU5408 (VEGFR2 Kinase Inhibitor I) is found to be the most potent and selective VEGFR2 inhibitor among the compounds. SU5408 (VEGFR2 Kinase Inhibitor I) shows little or no effect against receptors for platelet-derived growth factor, epidermal growth factor, or insulin-like growth factor (IC50>100 µM)[1].

청정 NLT 98%
저장 at 20ºC 2 years
*위의 정보는 참고 용입니다.

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