화학 이름 | Cyclo(Arg-Gly-Asp-D-Phe-Val) |
---|---|
화학 이름 | Cyclo(Arg-Gly-Asp-D-Phe-Val) |
CAS 번호 | 137813-35-5 |
MDL 번호 | MFCD00274410 |
분자식 | C26H38N8O7 |
분자 무게 | 574.63 |
Cyclo(Arg-Gly-Asp-D-Phe-Val) is an inhibitor of integrin αvβ3, with antitumor activity. IC50 & Target: αvβ3[1] In Vitro: Cyclo(Arg-Gly-Asp-D-Phe-Val) is an inhibitor of integrin αvβ3. Cyclo(Arg-Gly-Asp-D-Phe-Val) [c(RGDfV); 35 nM] induces disruption of leukemia cell migration and adhesion to leukemia osteoblasts in the 3D and 2D culture systems, affects the leukemia cell cycle and induces apoptosis in leukemia cells[1].
청정 | NLT 98% |
---|---|
저장 | at 20ºC 2 years |