Panidazole is an amoebicide. In Vitro: Panidazole in concentrations of 0.02-1 mM increases the mutation frequency of Klebsiella pneumoniae, Escherichia coli K12 and Citrobacter freundii to streptomycin resistance, including streptomycin dependence, in Luria and Delbrück's fluctuation test^[1]. In Vivo: In 100 cases of vaginal trichomoniasis treated with panidazole at the dose of 1.0 g per day for seven days in half of the patients and for 10 days in the other half, we obtained 50% and 60% cure rates^[3].