Chemical Name |
Zaprinast |
CAS Number |
37762-06-4 |
MDL Number |
MFCD00214073 |
Molecular Formula |
C13H13N5O2 |
Molecular Weight |
271.27 |
Synonyms |
M&B 22948 |
Introduction of 37762-06-4 :
Zaprinast (M&B 22948) is an inhibitor of cGMP-selective Phosphodiesterases(PDEs)[1]. Zaprinast is a G protein-coupled receptor (GPR) 35 agonist which activates rat GPR35 strongly and activates human GPR35 moderately[2]. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects[3]. IC50 & Target: PDE[1], GPR35[2]
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.