Chemical Name |
Kisspeptin-10, human |
CAS Number |
374675-21-5 |
MDL Number |
MFCD03452696 |
Molecular Formula |
C63H83N17O14 |
Molecular Weight |
1302.44 |
Introduction of 374675-21-5 :
Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression[1]. IC50 & Target: GPR54[1]
Angiogenesis[1] In Vitro: Kisspeptin-10 (KP-10) and its receptor GPR54 are key components in the regulation of GnRH secretion in humans and other mammals. Kisspeptin-10 protein binds to GPR54. Activation of Kisspeptin-10 suppresses pulmonary human melanoma and Kisspeptin-10 is a metastasis suppressor in breast cancer cells[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.