AY 9944
| Chemical Name | AY 9944 |
|---|---|
| CAS Number | 366-93-8 |
| MDL Number | MFCD01734586 |
| Molecular Formula | C22H30Cl4N2 |
| Molecular Weight | 464.30 |
Introduction of 366-93-8 :
AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol[1][2][3].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.