Safflower red, a red pigment, is isolated from safflower and used as a natural antioxidant in the food, cosmetics and clothing industries. In Vitro: Safflower red (Carthamin) is approved for use as a food supplement to improve hyperlipidemia, hypercholesterolemia, hypertension, and liver insufficiency. In addition, Safflower red is mainly used for making high-quality cosmetics, dyed cloth, and furniture^[1].