Chemical Name |
Piroxicam |
CAS Number |
36322-90-4 |
MDL Number |
MFCD00057317 |
Molecular Formula |
C15H13N3O4S |
Molecular Weight |
331.35 |
Synonyms |
CP-16171 |
Introduction of 36322-90-4 :
Piroxicam (CP-16171) is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively. IC50 & Target: IC50: 47 μM (COX-1, in human monocytes), 25 μM (COX-2, human monocytes)[1] In Vitro: Piroxicam (CP-16171) is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively[1]. Piroxicam (CP-16171) (167, 333, 500 μM) decreases cell population of T24 and the 5637 cells. Piroxicam (CP-16171) (500 μM) also reduces the cell viability of T24 and 5637 cell, and is significantly effective when combined with 0.05 μM carboplatin. The combination also inhibits Ki-67 expression in booth cells[3]. In Vivo: Piroxicam (CP-16171) (0.3 mg/kg qd 24-h p.o.) reduces tumor volume in 12 of 18 dogs, and such and effect is via induction of apoptosis and reduction in urine basic fibroblast growth factor concentration[2].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.