Chemical Name |
Dihydrosanguinarine |
CAS Number |
3606-45-9 |
MDL Number |
MFCD00872066 |
Molecular Formula |
C20H15NO4 |
Molecular Weight |
333.34 |
Synonyms |
13,14-Dihydrosanguinarine |
Introduction of 3606-45-9 :
Dihydrosanguinarine is a natural compound isolated from the leaves of Macleaya microcarpa; has antifungal and anticancer activity. IC50 value: Target: in vitro: Dihydrosanguinarine showed much less cytotoxicity than sanguinarine: at the highest concentration tested (20 microM) and 24h exposure, dihydrosanguinarine decreased viability only to 52% [1]. Dihydrosanguinarine showed the highest antifungal activity against B. cinerea Pers, with 95.16% mycelial growth inhibition at 50 μg/ml [2]. dihydrosanguinarine showed the most potent leishmanicidal activities (IC(50) value: 0.014 microg/ml, respectively) [4]. in vivo: Repeated dosing of DHSG for 90 days at up to 500 ppm in the diet (i.e. approximately 58 mg/kg/day) showed no evidence of toxicity in contrast to results published in the literature [3].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.