Chemical Name |
NNC 55-0396 |
CAS Number |
357400-13-6 |
MDL Number |
MFCD11878627 |
Molecular Formula |
C30H40Cl2FN3O2 |
Molecular Weight |
564.56 |
Synonyms |
NNC 55-0396 dihydrochloride |
Introduction of 357400-13-6 :
NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells. IC50 value: 6.8 nM Target: Cav3.1 T-type channel NNC 55-0396 can be an essential tool in preventing human ovarian cancer cell proliferation as a result of its ability to inhibit the function of T-type Ca2+ channels. It is believed that NNC 55-0396 may functions by dissolving in or passing through the plasma membrane of cells.
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.