Chemical Name |
Bifluranol |
CAS Number |
34633-34-6 |
MDL Number |
MFCD00864665 |
Molecular Formula |
C17H18F2O2 |
Molecular Weight |
292.32 |
Synonyms |
BX341 |
Introduction of 34633-34-6 :
Bifluranol (BX341) is an anti-androgen. IC50 & Target: Androgen Receptor[1] In Vivo: The absorption, distribution and excretion of Bifluranol have been studied in mouse, rat, ferret and dog; Bifluranol is readily absorbed following oral administration, but blood concentrations of Bifluranol are low due to hepatic uptake and biliary excretion. After intravenous administration of [3H]Bifluranol to rats (200 μg/kg) and ferrets (60 μg/kg) the blood concentrations of 3H decreases rapidly for the first 2 to 3 h, with the decrease being more rapid in females ( 18 min for rat, 30 min for ferret) than males (1.0 h for rat, 1.4 h for ferret). This is followed by a much slower decline (40 h for rat, 20 h for ferret) to concentrations at 96 h of less than 15 ng Bifluranol equivalents mL-1 (rat) or 1 ng Bifluranol equivalents mL-1 (ferret)[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.