Chemical Name |
Asoxime (dichloride) |
CAS Number |
34433-31-3 |
MDL Number |
MFCD00869535 |
Molecular Formula |
C14H16Cl2N4O3 |
Molecular Weight |
359.21 |
Synonyms |
HI-6 |
Introduction of 34433-31-3 :
Asoxime dichloride (HI-6) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride involves in modulating immunity response. Asoxime dichloride (HI-6) can be used as an antigen and improves vaccination efficacy in the nervous system[1]. IC50 & Target: IC50: acetylcholine receptors (AChRs)[1] In Vivo: Asoxime dichloride (intramuscular injection into the rear limb; 2% and 0.2% of median lethal dose 15.6 and 1.56 mg/kg; 21 or 65 days) significantly improved vaccination efficacy as a dose-dependent manner when KLH is 1 mg/kg. A combination of HI-6 and keyhole limpet hemocyanin (KLH) produces a vaccination of almost the same efficacy as that for Freund's complete adjuvant[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.