CAS No. 34391-04-3, Levalbuterol

Levalbuterol

NLT 98%
34391-04-3
DY549918
C13H21NO3
239.31
(R)-Albuterol;(R)-Salbutamol;Levosalbutamol

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Chemical Name Levalbuterol
CAS Number 34391-04-3
MDL Number MFCD00869868
Molecular Formula C13H21NO3
Molecular Weight 239.31
Synonyms (R)-Albuterol;(R)-Salbutamol;Levosalbutamol
Introduction of 34391-04-3 :

Levalbuterol ((R)-Albuterol; (R)-Salbutamol) is a short-acting β2-adrenergic receptor agonist and the active (R)-enantiomer of Salbutamol. Levalbuterol is a more potent bronchodilator than Salbutamol and has the potential for the treatment of COPD[1].
In Vitro: Levalbuterol (10 μM; 24 hours) induces 11β-HSD1 mRNA expression, however, it does not influence 11β-HSD2expression in airway epithelial cells[1].
Levalbuterol (10 μM; 24 hours) significantly reduces both LPS- and TNF-α-induced NF-κB activity while increasing GRE activation in an 11β-HSD1 dependent manner in a transformed mouse airway epithelial cell line[1].
In Vivo: Levalbuterol (subcutaneous injection; 1 mg/kg; 14 days) significantly decreases pulmonary inflammation in OVA mice, demonstrated a decrease in eosinophilia and IgE[3].

Purity NLT 98%
Storage at 20ºC 2 years
*The above information is for reference only.

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