Chemical Name |
Propafenone (hydrochloride) |
CAS Number |
34183-22-7 |
MDL Number |
MFCD00079243 |
Molecular Formula |
C21H28ClNO3 |
Molecular Weight |
377.90 |
Synonyms |
SA-79 (hydrochloride) |
Introduction of 34183-22-7 :
Propafenone (hydrochloride) (SA-79 (hydrochloride)) is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias. IC50 & Target: Sodium Channel[1]. In Vivo: Propafenone (hydrochloride) (SA-79 (hydrochloride)) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias. According to the Allergic Rhinitis and its Impact on Asthma (ARIA) treatment guidelines, intranasal anti-histamines are recommended for the first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis). Propafenone works by slowing the influx of sodium ions into the cardiac muscle cells, causing a decrease in excitability of the cells. Propafenone is more selective for cells with a high rate, but also blocks normal cells more than class Ia or Ib. Propafenone differs from the prototypical class Ic antiarrhythmic in that it has additional activity as a beta-adrenergic blocker which can cause bradycardia and bronchospasm[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.