Chemical Name |
I2906 |
CAS Number |
331963-29-2 |
MDL Number |
MFCD01128075 |
Molecular Formula |
C25H37N3O4 |
Molecular Weight |
443.58 |
Introduction of 331963-29-2 :
I2906 showed antimycobacterial and cytotoxic activity against mycobacterium tuberculosis. IC50 Value: Target: Antibacterial Under in vitro conditions, I2906 showed excellent antimycobacterial activities and low cytotoxicity. In a murine model infected with M. tuberculosis H37Rv, the reductions on bacterial loads of both lungs and spleen were statistically significant (p < 0.05) between I2906-treated mice and untreated controls after 4 weeks. Further, the colony-forming unit counts in the lungs were dramatically lower (p < 0.05) than that of isoniazid-treated mice by the addition of I2906 after 8 weeks. Moreover, survival rate was increased by I2906 treatment. For multidrug-resistant strain infection, bacterial counts were reduced significantly in the lungs and spleen due to I2906 treatment in comparison with data from untreated controls (p < 0.05).
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.