Chemical Name |
SU6656 |
CAS Number |
330161-87-0 |
MDL Number |
MFCD10565928 |
Molecular Formula |
C19H21N3O3S |
Molecular Weight |
371.45 |
Introduction of 330161-87-0 :
SU6656 is a Src family kinases inhibitor with IC50s of 280, 20, 130, 170 nM for Src, Yes, Lyn, and Fyn, respectively. SU6656 inhibits FAK phosphorylation at Y576/577, Y925, Y861 sites. SU6656 also inhibits p-AKT. In Vitro: SU6656 decreases phosphorylation of Src family kinases (SFKs) in HNSCC cells[2]. In Vivo: SU6656 (2-4 mg/kg; i.p.; once) significantly decreases ischemic postconditioning (IPoCo) mediated increase in fall down time[5].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.