Chemical Name |
Sulbutiamine |
CAS Number |
3286-46-2 |
MDL Number |
MFCD01726427 |
Molecular Formula |
C32H46N8O6S2 |
Molecular Weight |
702.89 |
Synonyms |
Bisibuthiamine |
Introduction of 3286-46-2 :
Sulbutiamine is a highly lipid soluble synthetic analogue of vitamin B1, used for the treatment of asthenia. In Vitro: Sulbutiamine shows neuroprotective effects on hippocampal CA1 pyramidal neurons subjected to oxygen-glucose deprivation. Sulbutiamine enhances electrophysiological properties such as excitatory synaptic transmissions and intrinsic neuronal membrane input resistance in a concentration-dependent manner[1]. Sulbutiamine attenuates apoptotic cell death induced by serum deprivation and stimulates GSH and GST activity in a dose dependent manner. Furthermore, sulbutiamine decreases the expression of cleaved caspase-3 and AIF[2].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.