Chemical Name |
NS19504 |
CAS Number |
327062-46-4 |
MDL Number |
MFCD01910159 |
Molecular Formula |
C10H9BrN2S |
Molecular Weight |
269.16 |
Introduction of 327062-46-4 :
NS19504 is a Ca2+-activated K+ channel (BK channel, KCa1.1 channel) activator (EC50=11.0 µM) with relaxing effect on bladder smooth muscle spontaneous phasic contractions[1]. IC50 & Target: EC50: 11.0 µM (BK channel)[1] In Vitro: NS19504 increases BK currents in freshly isolated guinea pig bladder smooth muscle cells and whole-cell. NS19504 increases the whole-cell currents response to 127 %, 194 %, 258 %, 561 % of control at a concentration of 0.32 µM, 1.0 µM, 3.2 µM and 10 µM, respectively[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.