Imetit (dihydrobromide)
32385-58-3
DY548591
C6H10N4S
170.24
VUF 8325 (dihydrobromide);SKF 91105 (dihydrobromide)
| Chemical Name | Imetit (dihydrobromide) |
|---|---|
| CAS Number | 32385-58-3 |
| MDL Number | MFCD00900700 |
| Molecular Formula | C6H10N4S |
| Molecular Weight | 170.24 |
| Synonyms | VUF 8325 (dihydrobromide);SKF 91105 (dihydrobromide) |
Introduction of 32385-58-3 :
Imetit dihydrobromide (VUF 8325 dihydrobromide) is a high affinity and potent agonist of histamine H3 and H4 receptors, with Ki values of 0.3 and 2.7 nM, respectively. Imetit mimics histamine effect in triggering a shape change in eosinophils (EC50=25 nM)[1][2][3]. In Vivo: Imetit dihydrobromide (2.5-10 mg/kg; i.p.) reduces the licking response induced by Apomorphine[4].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.