Chemical Name |
Gamma-Mangostin |
CAS Number |
31271-07-5 |
MDL Number |
MFCD00951752 |
Molecular Formula |
C23H24O6 |
Molecular Weight |
396.43 |
Synonyms |
γ-Mangostin |
Introduction of 31271-07-5 :
Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptors antagonist, purified from the fruit hull of the medicinal plant Garcinia mangostana. Gamma-Mangostin is a inhibitor of Transthyretin (TTR) fibrillization, it binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer[2]. Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 µM) [1]. IC50 & Target: 5-hydroxytryptamine 2A (5-HT2A) receptors[1]
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.