Chemical Name |
Amezinium (methylsulfate) |
CAS Number |
30578-37-1 |
MDL Number |
MFCD00865972 |
Molecular Formula |
C12H15N3O5S |
Molecular Weight |
313.33 |
Synonyms |
Amezinium metilsulfate;Lu-1631 |
Introduction of 30578-37-1 :
Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition ofnoradrenaline and tyramine uptake. Target: alpha and beta-1 receptors Amezinium metilsulfate is a sympathomimetic drug used for the treatment of low blood pressure. Cardiovascular effects of the new sympathomimetic Amezinium metilsulphate are investigated in 25 patients compared with a control group (n = 25). During spinal/epidural anaesthesia 5 mg amezinium is given i.v. if blood pressure dropped greater than 20 mmHg. from starting-point. A significant recovery of blood pressure (epidural anaesthesia: syst 21%, diast 9%; spinal anaesthesia: syst 13%, diast 6.6%) and a decrease in heart rate (6.8% resp. 4,5%) are thought due to peripheral vasoconstriction. Amezinium proves a stimulating drug for alpha- and beta 1-receptors by stabilising the systemic blood pressure in spinal/epidural anaesthesia.
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.