CAS No. 27741-01-1, Geniposidic acid

Geniposidic acid

NLT 98%
27741-01-1
DY545985
C16H22O10
374.34

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Chemical Name Geniposidic acid
CAS Number 27741-01-1
MDL Number MFCD00210294
Molecular Formula C16H22O10
Molecular Weight 374.34
Introduction of 27741-01-1 :

Geniposidic acid is an effective anticancer and radioprotection agent. Target: Others Mice were given an intraperitoneal injection of Geniposidic acid (GA) (12.5, 25, 50 mg/kg) 1 h before receiving GA against d-galactosamine (GalN) (800 mg/kg)/LPS (40 μg/kg). Liver and blood samples were collected 1 and 8 h after GalN/LPS injection. The survival rate of the GA group was significantly higher than the control. GalN/LPS increased serum aminotransferase activity, serum tumor necrosis factor-α level and hepatic lipid peroxidation and decreased hepatic glutathione content [1]. GA enhanced significantly the postirradiation responses of splenic blastogenesis by PHA. In addition, GA is a potent tumor growth inhibitor when combined with the X-irradiation, though there was no significant synergetic effect on their combined antitumor activity. The preliminary results of GA on hematological and blastogenic observations in this study suggested that it may very well, partially, play a role in an effective anticancer product with the ability to decrease undesirable radiation damage to the hematologic tissue after high dose irradiation [2].

Purity NLT 98%
Storage at 20ºC 2 years
*The above information is for reference only.

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