SEW2871
| Chemical Name | SEW2871 |
|---|---|
| CAS Number | 256414-75-2 |
| MDL Number | MFCD00096600 |
| Molecular Formula | C20H10F6N2OS |
| Molecular Weight | 440.36 |
Introduction of 256414-75-2 :
SEW2871 is a highly selective, orally active S1P1 agonist with an EC50 of 13.8 nM. SEW2871 activates ERK, Akt, and Rac signaling pathways and induces S1P1 internalization and recycling. SEW2871 reduces lymphocyte numbers in blood and has therapeutic implications in contexts of diabetes, Alzheimer’s disease, liver fibrosis, and inflammatory responses[1][2]. IC50 & Target: EC50: 13.8 nM (S1P1)[2]
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.