Sulfaclozine sodium (Sulfachloropyrazine sodium) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis)^[1]. IC50 & Target: Bacterial; Parasite^[1] In Vitro: The elimination of Sulfaclozine in the three systems: UV/TiO₂, UV/K₂S₂O₈, and UV/TiO₂/K₂S₂O₈. Sulfaclozine is weakly adsorbed on the surface of TiO₂ at pH 7 (< 5%) but efficiently eliminated with the following three systems: UV/TiO₂, UV/K₂S₂O₈, and UV/TiO₂/K₂S₂O₈ in ultra pure water. Moreover, 12 of Sulfaclozine by-products are identified and reaction pathways show that, in addition of ^•OH and SO₄^•− radicals, the conduction-band electrons are responsible for the formation of some main by-products either directly or by the formation of superoxide radicals^[2]. In Vivo: Sulfaclozine (60 mg/kg; intravenous injection or oral administration; male broiler chickens) can be used primarily for the treatment of parasitic and microbial infections of the digestive tract rather than for the treatment of systemic infections^[1].