Chemical Name |
Benznidazol |
CAS Number |
22994-85-0 |
MDL Number |
MFCD00243089 |
Molecular Formula |
C12H12N4O3 |
Molecular Weight |
260.25 |
Synonyms |
Ro 07-1051;Ro 71051 |
Introduction of 22994-85-0 :
Benznidazol (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease[1][2]. In Vivo: Benznidazole (100 mg/kg/day, p.o., 30 days) produces a decrease in electrocardiographic alterations, fewer modifications in the affinity and density of cardiac-receptors, and few isolated areas of fibrosis in the heart, in mice infected with Trypanosoma cruzi Tulahuen strain or SGO-Z12 isolate and treated at 180 days post infection (p.i.) (i.e. chronic phase) with Benznidazole[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.