Chemical Name |
Valategrast |
CAS Number |
220847-86-9 |
MDL Number |
MFCD18782681 |
Molecular Formula |
C30H32Cl3N3O4 |
Molecular Weight |
604.95 |
Synonyms |
R-411 (free base) |
Introduction of 220847-86-9 :
Valategrast (R-411 free base) is a potent and orally active integrin α4β1 (VLA-4) and α4β7 dual antagonist. Valategrast has the potential for Chronic obstructive pulmonary disease (COPD) and asthma treatment[1][2]. IC50 & Target: Integrin α4β1; Integrin α4β7[2] In Vitro: Valategrast contains a common l-phenylalanine-N-aroyl motif where the carboxylic acid is responsible for binding to the metal ion in the metal-ion-dependent adhesion site (MIDAS)[2].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.