Chemical Name |
CB30865 |
CAS Number |
206275-15-2 |
MDL Number |
MFCD00947652 |
Molecular Formula |
C26H22BrN5O2 |
Molecular Weight |
516.39 |
Synonyms |
ZM 242421 |
Introduction of 206275-15-2 :
CB30865(ZM 242421) is a potent inhibitor of Nampt , an enzyme present in the NAD biosynthetic pathway. IC50 value: Target: Nampt Cancer cells develop dependence on Nampt due to increased energy requirements and the elevated activity of NAD consuming enzymes such as sirtuins and mono and poly(ADP-ribose) polymerases (PARPs). These findings suggest new chemical starting points for Nampt inhibitors and further implicate this enzyme as a target in cancer.
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.