Chemical Name |
6-Alpha Naloxol |
CAS Number |
20410-95-1 |
MDL Number |
MFCD12031398 |
Molecular Formula |
C19H23NO4 |
Molecular Weight |
329.39 |
Synonyms |
Alpha-Naloxol |
Introduction of 20410-95-1 :
6-Alpha Naloxol(Alpha-Naloxol) is an opioid antagonist closely related to naloxone; a human metabolite of naloxone. IC50 value: Target: opioid antagonist When responding over the entire 30 min operant session was examined, naloxone was only 5-fold more potent than 6-alpha-naloxol in suppressing operant responding under Morphine Na ve conditions, but this increased to a 65-fold potency difference after Single or Repeat Morphine pretreatment. Examination of the relative potency of these antagonists in the Early Phase of operant testing (5-15 min post-antagonist) revealed an even greater 100-fold potency difference between naloxone and 6-alpha-naloxol, but in the Late Phase of testing (25-35 min post-antagonist), this had declined to a 9-fold potency difference, comparable to the relative potency of naloxone to 6-alpha-naloxol under Morphine-Na ve conditions.
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.