Chemical Name |
Ginkgolic Acid (C13:0) |
CAS Number |
20261-38-5 |
MDL Number |
MFCD01661602 |
Molecular Formula |
C20H32O3 |
Molecular Weight |
320.47 |
Synonyms |
Ginkgolic acid (13:0);Ginkgoneolic Acid;6-Tridecylsalicylic acid |
Introduction of 20261-38-5 :
Ginkgolic Acid (C13:0) is a natural anticariogenic agent in that it exhibits antimicrobial activity against S. mutans and suppresses the specific virulence factors associated with its cariogenicity. IC50 value: Inhibiting the biofilm formation of S. mutans (MBIC (50) = 4 μg/mL); reduced 1-day-developed biofilm of S. mutans by 50 % or more at low concentration (MBRC (50) = 32 μg/mL). Target: In vitro: Ginkgolic Acid (C13:0) inhibited not only the growth of S. mutans planktonic cells at minimum inhibitory concentration (MIC) of 4 μg/mL and minimum bactericidal concentration (MBC) of 8 μg/mL but also the acid production and adherence to saliva-coated hydroxyapatite of S. mutans at sub-MIC concentration. In addition, this agent was effective in inhibiting the biofilm formation of S. mutans (MBIC (50) = 4 μg/mL), and it reduced 1-day-developed biofilm of S. mutans by 50 % or more at low concentration (MBRC (50) = 32 μg/mL). Furthermore Ginkgolic Acid (C13:0) disrupted biofilm integrity effectively [1]. In vivo:
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.