Chemical Name |
Fmoc-Glu(2-phenylisopropyl ester)-OH |
CAS Number |
200616-39-3 |
MDL Number |
MFCD00672323 |
Molecular Formula |
C29H29NO6 |
Molecular Weight |
487.54 |
Synonyms |
Fmoc-Glu(OPp)-OH;Fmoc-Glu(O-2-PhiPr)-OH |
Glu-derivative for the selective modification of the γ-carboxyl group. The OPp group can be removed selectively in the presence of Boc/OtBu with 1% TFA/DCM. Ocampo et al. applied OPp protection during the synthesis of a peptide-oligonucleotide conjugate and cleaved it with 3% trichloroacetic acid in DCM. Tofteng et al. generated a backbone pyroglutamyl imide moiety from C-terminal Glu after selective on-resin OPp removal.
Purity |
NLT 98% |
Storage |
-20 ± 5 ºC |
*The above information is for reference only.