INH14
| Chemical Name | INH14 |
|---|---|
| CAS Number | 200134-22-1 |
| MDL Number | MFCD00158246 |
| Molecular Formula | C15H16N2O |
| Molecular Weight | 240.30 |
Introduction of 200134-22-1 :
INH14 is a cell permeable inhibitor of IKKα/IKKβ, with IC50s of 8.97 and 3.59 μM, respectively. INH14 inhibits the IKKα/β-dependent TLR inflammatory response. INH14 also inhibits downstream of TAK1/TAB1 and NF-kB pathways. Anti-inflammatory and anti-cancer activity[1]. IC50 & Target: IC50: 8.97 μM (IKKα), 3.59 μM (IKKβ)[1] In Vivo: INH14 (5 µg/g, i.p. for 2 hours) reduces lipopeptide-induced inflammation in mice[1].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.