Chemical Name |
Otamixaban |
CAS Number |
193153-04-7 |
MDL Number |
MFCD11100277 |
Molecular Formula |
C25H26N4O4 |
Molecular Weight |
446.50 |
Synonyms |
FXV673 |
Introduction of 193153-04-7 :
Otamixaban(FXV673) is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. IC50 value: Target: Factor Xa Otamixaban is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. In vivo experiments have demonstrated that Otamixaban is highly efficacious in rodent, canine and porcine models of thrombosis. In addition, recent clinical findings indicate that Otamixaban is efficacious, safe and well tolerated in humans and therefore has considerable potential for the treatment of acute coronary syndrome. This review article chronicles the discovery and pre-clinical data surrounding the fXa inhibitor Otamixaban as well as the recent clinical findings in humans.
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.