Chemical Name |
CGP71683 hydrochloride |
CAS Number |
192322-50-2 |
MDL Number |
MFCD07783999 |
Molecular Formula |
C26H30ClN5O2S |
Molecular Weight |
512.07 |
Synonyms |
CGP71683A |
Introduction of 192322-50-2 :
CGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a Ki of 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes. IC50 & Target: Ki: 1.3 nM (Y5 receptor), 200 nM (Y2 receptor), >4000 nM (Y1 receptor)[1] In Vitro: CGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a Ki of 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes[1]. In Vivo: CGP71683 (15 nmol/rat, icv, twice daily) shows anorexigenic effect, reducing food intake and bady weight of fed rats. CGP71683 causes 3-times higher serum total T4 and 37% increase in free T4 in the fasted rats than in the fasted controls rats[2].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.