N-ω-Hydroxy-L-norarginine acetate salt
189302-40-7
DY437777
C5H12N4O3
176.17
nor-NOHA;L-2-Amino-4-(2'-hydroxyguanidino)-butyric acid;H-Nar(OH)-OH
| Chemical Name | N-ω-Hydroxy-L-norarginine acetate salt |
|---|---|
| CAS Number | 189302-40-7 |
| MDL Number | MFCD01318777 |
| Molecular Formula | C5H12N4O3 |
| Molecular Weight | 176.17 |
| Synonyms | nor-NOHA;L-2-Amino-4-(2'-hydroxyguanidino)-butyric acid;H-Nar(OH)-OH |
N-ω-Hydroxy-L-norarginine (or N-ω-Hydroxy-nor-L-arginine) is a most potent reversible inhibitor of arginase. At pH 7.4 nor-NOHA inhibited the rat liver arginase-dependent hydrolysis of H-Arg-OH (E-1360) with an EC₅₀ = 2 ± 0.5 µM and the arginase activity of mouse macrophages with an EC₅₀ value of 50 ± 10 µM.
| Purity | NLT 98% |
|---|---|
| Storage | -20 ± 5 ºC |
*The above information is for reference only.