Ethacridine lactate is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor. IC50 & Target: PARG^[1] In Vitro: Ethacridine lactate is effective against mostly gram-positive species like Streptococci and Staphylococci and ineffective against gram-negative(P seudomonas aeruginosa)^[1]. Ethacridine Lactate is a safe abortifacient with about 80% success and hardly any side effects^[2]. In Vivo: The incidence of retained placenta is 16%. The extra-amniotic injection is a technically simple procedure and can be carried out even between 13-15 weeks of pregnancy when intraamniotic injection is difficult. Its bactericidal properties minimize the danger of post-abortal infection. It can be used in certain medical conditions like hypertension, bronchial asthma where hypertonic saline and prostaglandin are contraindi-cated^[2]. Ethacridine lactate performs better than other instillation abortion methods and it is a safe and effective method. Ethacridine lactate induces successful abortion in 92.8% of cases which is much higher than that found in the literature (about 82%). Abortion failure occurrs in the other 4 cases because of transverse lie of fetus, cervical dystocia, and uterine inertia^[2].