Chemical Name |
Valepotriate |
CAS Number |
18296-44-1 |
MDL Number |
MFCD00868024 |
Molecular Formula |
C22H30O8 |
Molecular Weight |
422.47 |
Synonyms |
Valtrate |
Introduction of 18296-44-1 :
Valepotriate, isolated from Valeriana jatamansi Jones, has anti-epileptic and anti-cancer activities[1][2]. In Vivo: Valepotriate showed significant anti-epileptic activity against MES- and PTZ-induced epilepsy at doses of 5, 10, and 20 mg/kg, and ED50 values for MES- and PTZ-induced epilepsy were 7.84 and 7.19 mg/kg, respectively. Furthermore, valepotriate (10 and 20 mg/kg) can significantly prolong sleeping time and shorten the latency time on the pentobarbital sodium-induced sleeping time test. Furthermore, valepotriate (5, 10, and 20 mg/kg) could significantly up-regulate the expression of GABAA, GAD65, and Bcl-2 and down-regulate the expression of caspase-3, but had no significant effect on the expression of GABAB[2].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.