SB228357
| Chemical Name | SB228357 |
|---|---|
| CAS Number | 181629-93-6 |
| MDL Number | MFCD00950378 |
| Molecular Formula | C22H17F4N3O2 |
| Molecular Weight | 431.38 |
Introduction of 181629-93-6 :
SB228357 is a selective, potent oral active 5-HT2C/2B receptor antagonist with pKi values of 6.9, 8.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. SB228357 has antidepressant/anxiolytic effects[1][2]. In Vivo: SB228357 (0-10 mg/kg; oral administration; for 90 minutes; male Sprague Dawley rats) treatment significantly reverses Haloperidol-induced catalepsy[2].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.