Chemical Name |
Tizoxanide |
CAS Number |
173903-47-4 |
MDL Number |
MFCD07484970 |
Molecular Formula |
C10H7N3O4S |
Molecular Weight |
265.25 |
Synonyms |
TIZ |
Introduction of 173903-47-4 :
Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities. IC50 value: Target: Antiviral agent in vitro: Tizoxanide inhibited virus replication of all CIVs with 50% and 90% inhibitory concentrations ranging from 0.17 to 0.21 μM and from 0.60 to 0.76 μM, respectively [2]. Nitazoxanide and its primary metabolite, tizoxanide, inhibit hepatitis C virus (HCV) replication in HCV replicon systems. Interestingly, serial passage in nitazoxanide or tizoxanide resulted in increased sensitivity to alpha interferon 2b: EC(50)s and EC(90)s were reduced three- and eightfold, respectively [3].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.