Chemical Name |
Boc-Asp(OBzl)-chloromethylketone |
CAS Number |
172702-58-8 |
MDL Number |
MFCD00672491 |
Molecular Formula |
C17H22ClNO5 |
Molecular Weight |
355.81 |
Synonyms |
Boc-Asp(OBzl)-CMK |
Boc-Asp(OBzl)-CMK penetrates cells and binds covalently to the active site of caspase-1 (ICE). At a concentration of 2.5 µM, this inhibitor reduces caspase-1-mediated processing of mature interleukin-1β in a monocytic cell line by 85 % without affecting tumor necrosis factor processing.
Purity |
NLT 98% |
Storage |
-20 ± 5 ºC |
*The above information is for reference only.