Chemical Name |
Efaproxiral (sodium) |
CAS Number |
170787-99-2 |
MDL Number |
MFCD02093864 |
Molecular Formula |
C20H22NNaO4 |
Molecular Weight |
363.38 |
Synonyms |
RSR13 sodium |
Introduction of 170787-99-2 :
Efaproxiral sodium is a synthetic allosteric modifier of haemoglobin (Hb), decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy. in vitro: Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity. Increasing tumor oxygenation reduces tumor radioresistance. Efaproxiral can enhance the oxygenation of hypoxic tumours and function as a radiation sensitiser, increasing the effectiveness of RT.
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.